Pancreatic cancer occurs when cells in the pancreas’s exocrine or endocrine glands mutate and grow rapidly. The endocrine gland secretes hormones into the bloodstream, and the exocrine gland secretes enzymes into the small intestine.
Although causes of pancreatic cancer can vary, some causes that have been pinpointed are certain genetic mutations and frequent smoking.
Symptoms include abdominal pain radiating to the back, weight loss, loss of appetite, jaundice, light stools, dark urine, itching, diarrhea, exacerbation of existing diabetes (or a new diagnosis of diabetes), fatigue, and blood clots.
Risk factors that increase chances of pancreatic cancer are smoking, diabetes, pancreatitis, genetic syndromes and mutations (such as the BRCA2 mutation, FAMMM syndrome, and Lynch syndrome), a family history, obesity, and old age.
Pancreatic cancer can be treated using immunotherapy, chemotherapy, radiation therapy, and surgery.